Endocrine Abstracts

MEN2a is a rare genetic endocrine disorder associated with mutation of RET oncogene on chromosome 10. It involves lesions in thyroid, parathyroid and adrenal glands. Medullary thyroid carcinoma is the pathological hallmark and usually the first presentation of this syndrome.Clinical case: A 64-year-old lady with previous history of hypertension, IHD, and hypercholesterolemia was referred to Endocrine clinic after she was incidentally found to have high c...

We are a presenting a 57 year old male victim of recurrent metastatic melanoma who was treated surgically in 2015 by wide local excision together with right axillary dissection for axillary nodal spread. He re-presented to dermatology clinic in December 2018 with skin lesion that was histologically proven to be a BRAF-mutant malignant melanoma. CT scans at that time showed spread to mediastinal and hilar nodes. Oncology team decided to commence Iplimumab/Nivolumab combination ...

Adrenal incidentalomata are a common finding on cross-sectional imaging of the abdomen. Further assessment is required to differentiate benign adrenal masses from adrenocortical carcinomas and hormone-secreting tumours. Phaeochromocytomas are rare catecholamine-secreting tumours arising from chromaffin cells of the adrenal medulla. They classically present with symptoms and signs of catecholamine excess including headache, sweating, hypertension and tachycardia. However, with ...